Eight proton conducting oxygen-deficient perovskites BaIn1−x−yTixZryO2.5+(x+y)/2−n(OH)2n with 0.2≤x+y≤0.5; 0≤n≤0.4 compounds were prepared by solid state reaction at 1350°C in air and studied by TGA, thermodiffraction, SEM and EIS. At low temperature, below 180°C, all compounds react with water vapor to incorporate protons. Hydration is associated with highly negative thermodynamic parameters. All the compounds present a disordered cubic symmetry except for the hydrated phases with the highest In content (x+y=0.2) which present a cubic to tetragonal transformation below 250°C. Phases are chemically stable towards moisture and 3% CO2 atmosphere in temperature and present thermal expansion properties compatible with standard fuel cell materials. At high temperature the conductivity is mainly anionic (σO2–≈0.01Scm−1 at 700°C) and below 600°C proton conductivity is observed. The best level of H+ conductivity was found for BaIn0.8Ti0.05Zr0.15O2.6 (at 400°C, σH+=2×10−3Scm−1). For this family of compounds, it is shown that the proton conductivity level at 400°C is correlated to the basicity and that good protonic conductors at low temperature are also good anionic conductors at high temperature.