In this article we present textile sensors for the continuous monitoring of electrocardiograms (ECG), made from fabrics coated with high electrically conductive poly(3,4-ethylenedioxythiophene) (PEDOT). Polymer coatings of PEDOT were in situ synthetized on plain weave fabrics of polyester by the vapour phase polymerization method, using aqueous oxidant solutions of Fe (III) chloride with a concentration of one molar, two polymerization layers and optimized process parameters. The coating provided fabrics with high electrical conductivity, characterized by a sheet resistivity of 10Ωsq−1. PEDOT coated fabrics and commercial conductive fabrics were made into sensors using a digital embroidery method. The performance of the sensors was analyzed by measurements of signal to noise ratio (SNR) under dry and moisture conditions and compared to those obtained with gel electrodes. The PEDOT sensors exhibited good performance characterized by SNR levels of the order to those obtained with gel electrodes. ECG sensors made of different types of fabrics exhibit significant differences in the noise amplitude, suggesting that the textile fibres and surface morphology are relevant parameters to consider in the sensoŕs design, affecting the contact resistance electrode—skin. The sensor’s resistance to washing cycles was tested under various temperature and detergent conditions. The experimental results indicate that the lifetime of the electrodes can be considerably enhanced with detergent solutions of dodecylbenzenesulfonate (DBS).