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Objective: Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disorder characterized by a slowly progressive ataxia and dysarthria. Anatomically, SCA6 was said to affect only the cerebellum. However, it has been argued that SCA6 may involve widespread regions of the brain. This study was designed to investigate the electrophysiological functions of the central nervous system in patients affected...
Objective: To characterize central motor conduction in relation to the clinical deficits and to the disease duration in 90 patients with acute relapsing-remitting MS (RR-MS) and in 51 patients with chronic primary or secondary progressive MS (P-MS).Methods: The triple stimulation technique (TST) was used to quantify the central motor conduction failure (expressed by the TST amplitude ratio) and conventional...
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