The dynamics of water in postmortem muscle were studied by magnetic resonance microscopy (MRM). Rabbit muscles were arterially injected with 3 and 5 M NaCl brine. T 2 and diffusion mapping were performed during the onset of rigor mortis. A wide spread of T 2 values and widely differing postmortem evolutions were observed for injected muscles, whereas T 2 was spatially homogeneous for intact muscle. Also, highly variable spatial distribution of diffusion coefficients along (D z ) and across (D x ) the muscle fibers was observed and diffusion anisotropy D z D x ) was less marked in injected muscles. The results indicate heterogeneity of brine distribution far from the injection site soon after injection. The postmortem evolution of the parameters is discussed in terms of structural changes induced by brine injection. MRM provides insight into how water dynamics respond to different NaCl concentrations inside muscle.