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Macrophages (Mφ) represent a dynamic cell population that develops and operates within a changing microenvironment. In parallel to Th1/Th2 cells, primary Mφ may undergo classical (Mφ1) or alternative (Mφ2) activation. Here, we investigated whether Mφ1/Mφ2 may be re-polarized by a secondary stimulation by Th1 or Th2 cytokines or by exogenous danger signals. We established that Mφ1 IFNγ ...
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