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Adjustable maintenance dosing with either budesonide/formoterol or budesonide was compared in asthma patients.This double-blind trial randomized 133 patients (mean forced expiratory volume in 1s 66% predicted) to receive 2 inhalations twice daily of budesonide/formoterol 160/4.5μg (640/18μg/day) or budesonide 320μg (1280μg/day) for 4 weeks. The study drug was adjusted in both groups according to symptoms...
In this economic evaluation, conducted alongside a randomized, double-blind clinical trial, economic data were collected from 339 patients with moderate-persistent asthma randomized to receive twice-daily, double-blind treatment with budesonide/formoterol 160/4.5μg in a single inhaler (n=166) or fluticasone propionate 250μg (n=173) for 12 weeks. The mean number of episode-free days (EFD) per patient...
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