To avoid the loss and accident caused by energy equipment failure, structural integrity monitoring requires precise sensors for measurement of stress and strain. Quantum dots (QDs)-epoxy resin composite shows variation of photoluminescence (PL) intensity under stretching. This paper presents three different phenomena of PL intensity during cyclic stretching. QDs-Epoxy Resin blank stretching and ANSYS calculation provide PL intensity tendency with strain transforming. Continuous cyclic loading after the PL intensity change becomes stable, illustrating a non-synchronized strain between metal and coating. The synchronous strain can be achieved in a wide application with the development of sensitive optical stress-strain sensors via optimization and characterization of QDs-Epoxy Resin.