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We compared the time course of tolerance to myocardial ischemia–reperfusion injury with the time course of heat shock protein 72 (hsp72; inducible form) induction after heat stress in a rat model. The size of the infarct resulting from ischemia–reperfusion was increased 12 h after whole-body hyperthermia (42°C for 15 min), but was significantly decreased 48 and 72 h after hyperthermia, compared with...
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