The second virial coefficients of Exp-6 chains are calculated using the Monte Carlo method. The results are presented as the scaled second virial coefficient B 2 /(m 2 σ 3 ) for various chain lengths m and repulsive-wall steepness parameters α at different scaled temperatures T ∗ . The scaled coefficient reduces and converges to a constant value as m→∞. Interestingly, the scaled coefficient scales as B 2 /(m 2 σ 3 )∝−α −1 , where the dependence reduces for larger m. The gyration radius increases with α, and in good solvent regime, scales like a self-avoiding chain when m→∞. The interaction energy between two chains depends on m, T ∗ , and α. With increasing m, the interaction becomes less repulsive. With increasing α or T ∗ , the repulsion between chains increases, and chains behave as they are in good solvent conditions. Moreover, the θ point decreases with increasing α and reducing m. Finally, the results are compared with the theoretical predictions using the PHSC model.