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A mononuclear ruthenium(II) complex, trans-[Ru(Hmel)2(dmso)2], was synthesized and characterized. The DNA- and BSA-binding properties of the mono-anionic meloxicam (Hmel−) ligand and its Ru(II) complex were investigated under physiological conditions. The interaction of the Hmel− ligand and the Ru(II) complex with fish sperm DNA were explored through UV–Vis spectroscopy, emission titration, and viscosity...
Hypoxia is a common feature of most solid tumors and its precise imaging is of great importance to therapy planning. Here we demonstrated that a ruthenium(II) anthraquinone complex [Ru(bpy)2(ipad)](ClO4)2 (Ru-ipad, where bpy=2,2′-bipyridine and ipad=2-(anthracene-9,10-dione-2-yl)imidazo[4,5-f][1,10]phenanthroline), is a powerful optical probe that can detect repeated cycles of hypoxia–normoxia in...
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