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Objectives: Fetal lung maturation in preterm infants with chorioamnionitis is known to be accelerated. However, the molecular basis of this pathological acceleration has not been elucidated. We investigated whether reactive oxygen species play a role in the acceleration of fetal lung maturation. Study Design: On the 16th day of gestation, xanthine (1mM) and xanthine oxidase solution (0.1-100mU/ml)...
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