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The Lascaux Cave was discovered in 1940, and by 1960 it had received up to 1800 daily visitors. In 1963, the cave was closed and in 2001 it was invaded by a Fusarium solani species complex which was treated for four years with benzalkonium chloride. However, Lascaux Cave bacteria have only been poorly investigated. Here we show that the cave is now a reservoir of potential pathogenic bacteria and...
This research presents the first extensive mutational study of N-terminal amino acids necessary for activity of a bacterial Zeta class glutathione transferase (GST). Our studies on UG30 tetrachlorohydroquinone reductive dehalogenase (PcpC) revealed that, similar to other Zeta class GSTs, N-terminal Ser and Cys residues play critical roles in glutathione binding and their mutation results in functional...
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