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The experience of preoperative irradiation in clinically locally advanced rectal cancer for the period 1991–2003 is reported. Prognostic factors for survival and recurrence, and parameters for obtaining a free circumferential margin were evaluated.A prospective cohort study of 204 M0 patients given >45Gy preoperatively (median age 66years; 29% women; tumour level <16cm from the anal verge).Multivisceral...
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