Whereas Operations Research concentrates on optimization, practitioners find the robustness of a proposed solution more important. Therefore this paper presents a practical methodology that is a stagewise combination of four proven techniques: (1) simulation, (2) optimization, (3) risk or uncertainty analysis, and (4) bootstrapping. This methodology is illustrated through a production-control study. That illustration defines robustness as the capability to maintain short-term service, in a variety of environments (scenarios); that is, the probability of the short-term fill-rate remains within a prespecified range. Besides satisfying this probabilistic constraint, the system minimizes expected long-term work-in-process. Actually, the example compares four systems--namely, Kanban, Conwip, Hybrid, and Generic--for the well-known case of a production line with four stations and a single product. The conclusion is that in this particular example, Hybrid is best when risk is not ignored; otherwise Generic is best; that is, risk considerations do make a difference.