The objective of this study is to provide a framework for relocating or reconfiguring existing pollution monitoring station networks by using feature selection and data mining techniques. This methodology enables a partial redesign based on the maximization of the available information that is gathered by the pollution networks by the optimal data mining technique. It also considers requirements of the decision makers, like potential target places, etc.Since this methodology is based on the quality of forecasting, it can also be useful for auditing and forecasting. A case study is included in this paper. In light of the prediction results, a new way to relocate the existing monitoring station is proposed.