A variable polarity cold metal transfer (VP-CMT) arc power source with different arc modes was employed in additive manufacturing Al-6Mg alloy parts. The microstructures were characterized using scanning electron microscopy with electron back-scattered diffraction. Even equiaxed grains in size of 20.6–28.5µm with random orientation were obtained under VP-CMT mode, while a large number of columnar grains in bigger size exist in samples under other arc modes. Tensile strength of the VP-CMT sample with a maximum of 333MPa is higher than that of the Al-6Mg wrought alloys due to fine-grain strengthening. However, the tensile strength of the VP-CMT sample in different tensile direction was anisotropic, with a percentage of 8–27%. The comprehensive analysis of defects and grain orientation showed that the micro pores in interlayer pore region lead to the anisotropy.