The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The precise relationship between the length of the 3′ poly(A) tail and the replication and infectivity of poliovirus RNA was examined in this study. With both poly(A) 11 and poly(A) 12 RNAs, negative-strand synthesis was 1–3% of the level observed with poly(A) 80 RNA. In contrast, increasing the length of the poly(A) tail from (A) 12 to (A) 13 resulted in about...
Poliovirus 2A pro is required for the inhibition of host cell protein synthesis and efficient viral replication. We investigated the role of 2A pro in regulating viral RNA stability, translation and replication in HeLa S10 reactions. The protease activity of 2A pro or its polyprotein precursors, 2AB or P2, was required to increase the stability of viral RNA and prolong translation...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.