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The aims of this study were to modulate inflammation in synovial explants with the compounds: dexamethasone, rapamycin, bone morphogenetic protein 7 (BMP-7) and pravastatin, and to investigate the modulatory capacity of the compounds on specific macrophage phenotypes.Synovial explants from osteoarthritis (OA) patients were treated with 10−6 M dexamethasone, 100 ng/mL rapamycin, 500 ng/mL BMP-7 or...
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