In this paper, reactive brilliant X-3B was used as a model compound to study the photocatalytic activity of TiO 2 . Experimental results showed that the adulteration of iron and silver on TiO 2 could greatly improve the activity of TiO 2 , and the optimum adulteration amount of iron and silver was 0.1wt.% (Fe/TiO 2 ) and 0.05wt.% (Ag/TiO 2 ), respectively, at the adulteration range of experiments. The photocatalytic degradation kinetics of X-3B on TiO 2 , Fe/TiO 2 and Ag/TiO 2 were also studied. The results showed that the degradation of X-3B on all of them were in accordance with the Langmiur–Hinshelwood kinetics model well, and the sequence of apparent reaction rate constants k of X-3B degradation catalyzed by TiO 2 , Fe/TiO 2 and Ag/TiO 2 was Ag/TiO 2 >Fe/TiO 2 >TiO 2 , while adsorption equilibrium constants K A of X-3B on Fe/TiO 2 and Ag/TiO 2 were approximately the same, and both were greater than that of TiO 2 .