A good scientist develops within a context. There is the context of the chosen discipline itself. This encompasses the uncertainties and challenges of unresolved questions in that discipline, which may inspire and stimulate the scientist to search and research again. Just as important, there is the personal context of the individual. This background may be composed of many elements; some may relate to personal history or be due to influences from mentors, other interests and talents. This paper seeks to demonstrate the rich and varied influences that have played a part in Professor Malcolm Molyneux's life and have informed him as a medical scientist, as well as played a part in his contribution to academic developments in Malawi, with particular reference to the College of Medicine at the University of Malawi.