Glycine and glycerol were used as the model compounds of protein and fattiness, respectively. A continuous tubular-flow reactor was used for the gasification experiments operated at 380–500°C and 25MPa with or without Na 2 CO 3 catalyst. Compared with a negative effect on glycerol gasification, Na 2 CO 3 could increase hydrogen yield and Chemical Oxygen Demand (COD) destruction efficiency, and the catalytic performance of 0.1wt% Na 2 CO 3 was better than that of 0.2wt% for glycine gasification. When 1wt% glycine solution with 0.1wt% Na 2 CO 3 , or 1wt% glycerol solution without Na 2 CO 3 was gasified at 500°C with the residence time of 0.98min, their corresponding gasification efficiencies were up to 95.8% and 98%, and hydrogen yields could reach 4.14 and 5.08mol/mol, respectively. Hydrogen molar fraction in gaseous product was about 60% and liquid effluents could be reutilized. Correspondingly, the ideal overall reaction equations for glycine and glycerol gasification were proposed.