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To understand the neural bases of memory it is necessary to localize the regions storing information. Part of the hyperstriatum ventrale (IMHV) serves such a function for the learning process of imprinting in domestic chicks. Chicks exposed to an object learn its characteristics, and in doing so, the responsiveness of IMHV neurones to that object is selectively enhanced. Imprinting is associated...
Clathrin-mediated endocytosis at the plasma membrane is a major pathway of synaptic vesicle recycling in neurones, but little is known about the molecular machinery that orchestrates the process. The amphiphysin protein has recently emerged into the limelight since its discovery in 1992 as a synaptic vesicle-associated protein. It was subsequently found to interact in vitro with the GTPase dynamin...
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