Predictions of the gas temperature and pressure profiles are vital to the design and operation of gas transmission lines. Available analytical methods for the calculation of these profiles are evaluated and a numerical framework for the rigorous calculation has been developed. The predictions from both the analytical and numerical procedure have been compared to field data from the Iranian Gas Trunk-lines (IGAT). These comparisons showed that all the available methods were tuned using data obtained from small to medium diameter pipes extrapolated poorly to large diameter pipelines. In order to improve the predictions for large diameter pipelines, the effect of model parameters such as soil thermal conductivity, pipe relative roughness and velocity profile correction factor has been evaluated. The results show that temperature and pressure profiles at high Reynolds number are sensitive to the Fanning friction factor; however, thermal conductivity and velocity distribution correction factor have almost no effect on the temperature and pressure profiles provided these parameters were set at an average acceptable industry value. Since the pressure profile for large diameter pipes was most sensitive to the Fanning friction factor a parameter optimization method was used to fine-tune the Fanning friction factor as a function of Reynolds number at an average accepted industry relative pipe roughness.