The aim of this study is to formulate a computational fluid dynamics (CFD) model that can illustrate the fully turbulent flow in a pipe at higher Reynolds number. The flow of fluids in a pipe network is an important and widely studied problem in any engineering industry. It is always significant to see the development of a fluid flow and pressure drop in a pipe at higher Reynolds number. A finite volume method (FVM) solver with k–ε turbulence model and enhanced wall treatment is used first time to investigate the flow of water at different velocities with higher Reynolds number in a 3D pipe. Numerical results have been presented to illustrate the effects of Reynolds number on turbulence intensity, average shear stress and friction factor. Friction factor is used to investigate the pressure drop along the length of the pipe. The contours of wall function are also presented to investigate the effect of enhanced wall treatment on a fluid flow. A maximum Reynolds number is also found for which the selected pipe length is sufficient to find a full developed turbulent flow at outlet. The results of CFD modeling are validated by comparing them with available data in literature. The model results have been shown good agreement with experimental and co-relation data.