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Occupational exposures to respirable dusts contaminated with the mycotoxin aflatoxin B 1 (AFB 1 ) have been associated with an increased incidence of upper airway tumors. To investigate this possible etiology we compared the abilities of tracheal and lung S9 from rabbit, hamster and rat to activate AFB 1 to mutagens in Salmonella typhimurium TA 98. The activation of AFB ...
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