Four new constituents; two benzofuran glucosides (picraquassiosides A and B), a neolignan (picraquassioside C) and a phenol (picraquassioside D) were isolated from fresh fruits of Picrasma quassioides, together with seven known compounds. The structures of the new compounds were elucidated as 6-hydroxy-4-methoxy-5-benzofuranpropionic acid 6-O-β-d-glucopyranoside, 6-hydroxy-4,7-dimethoxy-5-benzofuranpropionic acid 6-O-β-d-glucopyranoside, 1-(4 -O-glucopyranosyl-4 -hydroxy-3 -5 -dimethoxyphenyl)-2{2 ,6 -dimet hoxy-4 -[1-(E) propen-3-ol]-phenoxy}-propan-1,3-diol(threo), and methylphloroglucinol β-d-glucopyranoside by spectroscopic means.