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We studied the association of symptoms with attitudes toward sexuality, life-style, family functioning, and follicle-stimulating hormone (FSH) levels in perimenopausal women. We collected data on depression, anxiety, nonspecific index of depression, and the empty nest syndrome in 222 women with a mean age of 47.7 (47.2-48.2, 95% CI) years (102 of them were at menopause). Family functioning was evaluated...
Although hormonal response abnormalities in depression have been demonstrated in several hypothalamic-pituitary-target organ axes after a variety of neuroendocrine challenge tests, studies of hypothalamic-pituitary-gonadal (HPG) axis function have been inconsistent in their findings. The use of maximal or supramaximal doses of gonadotropin-releasing hormone (GnRH) in early studies (150-600 μg) may...
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