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Vicriviroc (VCV), a small-molecule antagonist of the C–C chemokine receptor 5 (CCR5), blocks HIV's entry into CD4+ cells. Small studies have suggested that resistance to CCR5 antagonists is slow to develop.To examine resistance to VCV in isolates from treatment experienced patients who experienced virologic failure in two phase 3 trials.Genotypic and phenotypic susceptibility to VCV, and other antiretroviral...
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