This study presented a model of the absorption of carbon dioxide by mono-ethanolamine solution in a rotating packed bed absorber using two-film theory for mass-transfer. It was found that temperature bulge can also be found in rotating packed bed if large amount of carbon dioxide was removed. Proper accounting of changes in liquid holdup is critical to accurate prediction of changes in capture efficiencies with gas and liquid flow rate. Moreover, use of a modified expression for the apparent kinetic constant in the enhancement factor is necessary to predict experiment results using high amine concentrations. Since the model have been comprehensively validated using data provided by various authors in the literature with various gas–liquid flow rates, rotator speeds, and solvent conditions, it could be used as a tool for scale up studies.