Personalized Medicine Universe

Items from 1 to 18 out of 18 results

article

Treating relapsing carcinoma with high-quality image-guided intensity-modulated radiation therapy using the TomoTherapy treatment system

Yukimasa Aoki

Personalized Medicine Universe > 2012 > 1 > 1 > 33-38

The purpose of this study was to examine solutions to the clinical problems that are suffered by patients. By employing sequential image-guided intensity-modulated radiation therapy (herein referred to as IGIMRT), the patients were observed and compared from the perspectives of various elements: Biochemical non-evidence of disease (bNED), Prostate-Specific Antigen (PSA), Quality of Life (QOL), etc...

article

Development of a smartphone-based diabetes self-care management system

Sang Youl Rhee, Jeong-taek Woo, Young Seol Kim, Young Kil Choi

Personalized Medicine Universe > 2012 > 1 > 1 > 85-86

article

High-dose intravenous vitamin C improves quality of life in cancer patients

Hidenori Takahashi, Haruyoshi Mizuno, Atsuo Yanagisawa

Personalized Medicine Universe > 2012 > 1 > 1 > 49-53

High-dose intravenous vitamin C (IVC) therapy has been safely employed for at least 30 years as one form of complementary alternative medical treatments for cancer. We prospectively examined the effects of IVC on the quality of life (QOL) in cancer patients in a multicenter observational study.This study involved 60 patients with newly diagnosed cancer who visited participating institutions in Japan...

article

Retrospective analysis of the clinical efficacy of a dendritic cell-based cancer vaccine in patients with advanced or recurrent breast cancer

Shinichiro Akiyama, Ariko Yamauchi, Teruyo Yamashita, Hiroshi Nimura, more

Personalized Medicine Universe > 2012 > 1 > 1 > 25-32

Tumor-specific cytotoxic T lymphocytes can be efficiently activated in vivo by dendritic cell (DC)-based vaccination. This trial assessed the clinical efficacy and toxicity of DC-based immunotherapy in patients with advanced breast carcinoma.DC-based immunotherapy (DC vaccine alone or DC vaccine plus lymphokine-activated natural killer (NK) cell therapy) was administered to 26 patients with unresectable...

article

Japanese herbal medicine for weight loss in a morbidly obese patient: A case report

Izumi Haruta, Akihiro Asakawa, Masako Nakano, Miki Mukai, more

Personalized Medicine Universe > 2012 > 1 > 1 > 77-78

Here, we report a case in which the use of bofu-tsusho-san (BF) was effective for weight loss. A 22-year-old woman with a height of 157 cm, weight of 154.8 kg, and body mass index (BMI) of 63.6 kg/m ² was hospitalized. We limited her dietary calories and prescribed exercise, but there was little resulting decrease in her body weight. We administered BF as an anti-obesity drug. Following BF...

article

Regulatory role of natural killer (NK)-T cells for EAE

Rong-Rong Song, Huan-Ren, Wei Sun, Xu-Wen, more

Personalized Medicine Universe > 2012 > 1 > 1 > 18-24

NK1.1+ natural killer (NK)-T cells reactive to CD1 appear to be involved in spontaneous autoimmune disease, but their role in induced autoimmune disease remains unclear. While we previously reported a regulatory role of NK cells in experimental autoimmune encephalomyelitis (EAE), we demonstrate here that NK-T cells would also play a pivotal role in the control of EAE. C57BL/6 (B6) mice selectively...

article

Preface

Hiroyuki Abe

Personalized Medicine Universe > 2012 > 1 > 1 > 1

article

Amycenone, a nootropic found in Hericium erinaceum

Kazutoyo Inanaga

Personalized Medicine Universe > 2012 > 1 > 1 > 13-17

The current paper describes the physiological and nootropic actions of Amycenone, which is an activator of brain function that is obtained from extracts of the Yamabushitake (Hericium erinaceum).Kawagishi and his group have studied compounds that are derived from medicinal mushrooms and their use in the treatment of dementia since 1991. They have found that H. erinaceum exerts important bioactivities,...

article

System lupus erythematosis and mercury toxicity

John P. Salerno

Personalized Medicine Universe > 2012 > 1 > 1 > 81-83

This case study examines the relationship between heavy metal toxicity and its influence on auto immune disease. In the traditional medical world almost all auto immune diseases are classified as idiopathic. In my clinical experience with hundreds of auto immune disease patients, it is increasingly clear that environmental influences particularly heavy metals and most commonly mercury is a major causative...

article

Do dental implants cause scoliosis?: A case report

Yoshiro Fujii

Personalized Medicine Universe > 2012 > 1 > 1 > 79-80

Many cases of scoliosis are idiopathic, and therefore the causes have yet to be clarified. Subject A had experienced involuntary contortions of her spine and discomfort for 3 years. She also experienced difficulty when breathing, particularly at night, and, as a consequence, frequently suffered from insomnia. When a titanium implant was brought close to her body, her spinal column began to twist....

article

Vitamin C concentration in intracellular free radical oxidation–reduction reactions and chemical shift—Potential for the quantitative analysis of ATP in a mitochondrion

Masayuki Oshima

Personalized Medicine Universe > 2012 > 1 > 1 > 58-69

Phosphorylation in the cell nucleus is closely associated with cell death during the cell-division cycle. Since the discovery that the phosphorylation process is inhibited by radiation exposure, it has been believed that radiation exposure causes disorder in the electron transfer system. It is believed that vitamin C activates the electron transfer system. Vitamin C has been confirmed to kill cancer...

article

Seeing schizophrenia through a personalized medicine prism

Isaac L. Michael Lesser

Personalized Medicine Universe > 2012 > 1 > 1 > 84

article

Personalized cancer therapy for stage IV non-small cell lung cancer: Combined use of active hexose correlated compound and genistein concentrated polysaccharide

Reiki Ishizuka, Hajime Fujii, Takehito Miura, Yukiko Fukuchi, more

Personalized Medicine Universe > 2012 > 1 > 1 > 39-44

This study aims to provide a strategy for personalized cancer therapy that results in increased survival time with better and more stable quality of life (QOL).Active hexose correlated compound (AHCC) and genistein concentrated polysaccharide (GCP) were administered to patients diagnosed with stage IV non-small cell lung cancer (NSCLC) with distant metastasis (M1). AHCC and GCP were consumed orally...

article

Epigenetics in cancer and inflammation

Hiroaki Kawasaki, Hiroyuki Abe

Personalized Medicine Universe > 2012 > 1 > 1 > 7-12

Epigenetics has a critical role in various events in both normal development and human disease. DNA methylation, a major epigenetic modification, regulates gene expression at the transcriptional level. In this review, to understand epigenetics we focus on DNA methylation in molecular biology and human disease.We selected 105 reports related to DNA methylation in molecular biology or human disease...

article

Mind–body medicine: Effect of the mind on gene expression

Eriko Takimoto-Ohnishi, Junji Ohnishi, Kazuo Murakami

Personalized Medicine Universe > 2012 > 1 > 1 > 2-6

Positive emotions via laughter or meditation contribute to physiological and psychological health. In this review, we summarize how positive emotions affect gene expression in humans and an animal model.Our first studies demonstrated that mirthful laughter reduced a postprandial elevation in blood glucose levels in type II diabetes patients and increased the expression of genes related to natural...

article

Activated charcoal as an effective treatment for bacterial vaginosis

Kunihiko Tominaga, Shigehiro Sato, Masayuki Hayashi

Personalized Medicine Universe > 2012 > 1 > 1 > 54-57

Bacterial vaginosis is one of the most common infectious disorders that affect women of reproductive age. For many years, antibiotics have been used for the treatment of this infection. However, antibiotics may adversely affect the normal vaginal bacterial flora. Therefore, development of treatments without adverse effects is urgently required. The aim of this study was to evaluate the efficacy of...

article

Stimulation of dermal fibrous tissue in malignant and chronic diseases: A novel therapeutic approach based on energy medicine

Tsuyoshi Hashimoto

Personalized Medicine Universe > 2012 > 1 > 1 > 70-76

Despite the development of various therapeutic methods for malignant and chronic diseases, it remains difficult to cure or achieve satisfactory remission in several of them. Therefore, a novel therapeutic methodology is strongly wanted for such diseases. My aim was to develop a novel therapeutic maneuver for use as supplemental therapy.After examination of the skin pattern in the back, a needle was...

article

Role of traditional Japanese medicines in the relief effort in areas affected by the Great East Japan Earthquake

Hajime Nakae

Personalized Medicine Universe > 2012 > 1 > 1 > 45-48

The medical system of the Tohoku region was disrupted by the Great East Japan Earthquake on March 11, 2011. Akita University Hospital provided medical support to earthquake-affected areas in Rikuzentakata City, Iwate Prefecture. The 11th team, out of 27 Akita University Hospital Medical support teams, provided medical support service including Kampo, traditional Japanese medicine, from April 17 to...

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CANCER (2)
ACTIVATED CHARCOAL (1)
ADVANCED PROSTATE CANCER (1)
AHCC (1)
ALTERNATIVE TREATMENT (1)
ANTIBIOTICS (1)
ATYPICAL ANTI-PSYCHOTICS (1)
BACTERIAL VAGINOSIS (1)
BIOMARKER (1)
BNED (1)
BOFU-TSUSHO-SAN (BF) (1)
BREAST CARCINOMA (1)
CELL PHONE (1)
CHEMICAL BOND (1)
COGNITIVE IMPAIRMENT (1)
COLLAGEN (1)
DC-BASED CANCER VACCINE (1)
DERMAL STRANDS (1)
DNA METHYLATION (1)
EBM (1)
ELECTROMAGNETIC WAVE HYPERSENSITIVITY (1)
ENVIRONMENTAL TOXINS (1)
EPIGENETICS (1)
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (1)
FREE ENERGY CHANGE (1)
FREE RADICAL (1)
GCP (1)
GENE EXPRESSION PROFILE (1)
HEAVY METALS (1)
HERICIUM ERINACEUM (1)
IMMUNE THERAPY (1)
IMPLANT (1)
INFLAMMATION (1)
INTRAVENOUS VITAMIN C (1)
JAPANESE HERBAL MEDICINE (1)
KAMPO MEDICINE (1)
LACTOBACILLI (1)
LAUGHING RAT (1)
LAUGHTER (1)
LEAD POISON (1)
LOCAL CONTROL (1)
MALIGNANCY (1)
MEDICAL SUPPORT SYSTEM (1)
MEDITATION (1)
MERCURY OVERLOAD (1)
MIND–BODY MEDICINE (1)
MUC1 (1)
NEOPLASMS (1)
NERVE GROWTH FACTOR (NGF) (1)
NK (1)
NK-T CELL (1)
NOOTROPIC (1)
NSCLC (1)
NUTRITION (1)
OBESITY (1)
PLASMA (1)
QOL (1)
QUALITY OF LIFE (1)
RESTING METABOLIC RATE (RMR) (1)
RIORDAN PROTOCOL (1)
SCHIZOPHRENIA (1)
SCOLIOSIS (1)
SENSITIVITY TO COLD (1)
SEQUENTIAL IMAGE-GUIDED INTENSITY-MODULATED RADIATION THERAPY (1)
THE GREAT EAST JAPAN EARTHQUAKE (1)
TOMOTHERAPY (1)
TRADITIONAL JAPANESE MEDICINES (1)
VITAMIN THERAPY (1)
WT1 (1)
Β-DECAY (1)
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