Mineralogical studies revealed that the stream sediments in northwestern Saudi Arabia between Duba and Al Wajh on the Red Sea coast are auriferous and can represent a potential source of easily recoverable placer gold. The detailed ore microscopic study supported by fire assay data of stream sediments at the southern sector of Duba-Al Wajh (Wadi Al Miyah, Wadi Haramil and Wadi Thalbah) in NW Saudi Arabia show economic concentrations of gold in their silt fraction (40–63μm). However, particles of extremely fine “dusty” gold (⩽40μm in size) are identified in most stations as independent grains. The maximum gold content in the samples of Wadi Al Miyah is 13.61wt% which is reported for the light fraction (⩽40μm). Maximum gold content in the heavy fractions of Wadi Haramil stream sediments amounts 6.90g/t Au in a relatively coarse fraction (63–125μm). The size still fulfills the silt fraction, but the coarsening of gold can be correlated with either original size of native gold in the Neoproterozoic mineralized zone or/and distance of transportation. It appears that the most gold-rich fractions of the analyzed samples are those from Wadi Thalbah. They have the highest index figure, which suggests that its placer gold may be economically exploitable. Gold content in the heavy fractions of samples from Wadi Thalbah is high and lies within a wide range (6.27–28.83g/t), except for a single sample collected at the upstream with 0.77g/t Au only.Fire assay data of samples from three wadis at the northern sector show that their gold content is clearly lower than in the samples from the southern sector. Only few samples from Wadi South Marwah are promising because they contain reasonable gold content (3.10–3.60g/t) before heavy liquid separation. The two samples give gold content up to 11.03g/t in their heavy mineral concentrate. The heavy fractions from both Wadi Al Amud and Wadi Salma are poor in gold where the maximum content of the metal in these concentrates are 1.32 and 1.17g/t, respectively. Generally, the heavy mineral concentrates of both wadis contain ⩽1g/t Au which is presently uneconomic. Generally, fire assay data of gold proved that samples from the wadis in the southern sectors are more promising for future gold exploration and exploitation.