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Objective: We investigated the influence of different edible oils high in oleic acid but with different unsaponifiable fractions on the fatty acid composition and lipid peroxidation in plasma and low-density lipoprotein (LDL) in rabbits.Methods: Thirty-two rabbits were randomly assigned to four groups of eight animals. For 8 wk each group was fed a semisynthetic isoenergetic diet that differed by...
OBJECTIVE: We previously demonstrated the beneficial effects of dietary flavonoids derived from the ethanolic extract of licorice root against atherosclerotic lesion development in association with inhibition of low-density lipoprotein (LDL) oxidation in atherosclerotic mice. Administration of licorice extract to normolipidemic subjects also inhibited LDL oxidation. In the present study, we extended...
The effects of α-ketoglutarate (α-KG) on hyperammonemia induced by ammonium acetate were studied biochemically in experimental rats. The levels of circulatory urea and non-protein nitrogen increased significantly in rats treated with ammonium acetate and decreased significantly in rats treated with α-KG and ammonium acetate. In liver and kidney tissues, similar patterns of alterations across groups...
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