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Ni 2+ , a toxic, carcinogenic and allergenic agent, affected both the kinetic and chemical courses of the Fe 2+ -induced oxidation of arachidonic acid (AA) in 0.05 M phosphate buffer (pH 7.4) and at 37 o C. At 10 μM concentration, Ni 2+ decreased the rate of oxidation of peroxide-free AA (200 μM) promoted by 50 μM Fe 2+ , as determined by...
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