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The antineoplastic bifunctional-alkylating agent busulfan (Bu) induces developmental anomalies. We examined histopathological changes in the molar roots of rats that received Bu at different stages of root formation.At different developmental stages, i.e., on postnatal days (P) 13, 15, and 19, rats were administered 7.5mg/kg of Bu dissolved in dimethyl sulfoxide (DMSO) and then killed on P 30. After...
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