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The expression of GABA A receptors and the effects of GABAA receptor agonists on the response properties of tongue afferent fibres were investigated in female rats to determine if peripheral GABA receptors might be a target of topical benzodiazepines when used for pain relief in burning mouth syndrome patients.Nerve fibres in tongue sections from six female rats were identified using protein...
To explore the involvement of synaptic plasticity in pain induced by experimental tooth movement, we evaluated the expression of protein kinase M zeta (PKMζ), an enzyme necessary for maintaining long-term potentiation (LTP) in the anterior cingulate cortex (ACC).Male Sprague-Dawley rats weighing 250–300g were used. The change of the expression of PKMζ in the ACC was measured by western blot, and the...
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