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Usually practicing veterinarians and animal keepers have to deal with inadequate supplementation of copper which causes deficiency diseases. However, instead of curing, the consequential intake of copper is likely to cause copper intoxication. Copper poisoning is observed particularly frequently, in sheep - the most sensitive domestic animal to copper toxicity. In most cases, sheep undergo chronic...
The aim of the study was to establish the optimal methods for hypothermic storage of equine isolated hepatocytes. Viability of equine isolated hepatocytes after hypothermic storage was dependent on the type of storage medium as well as on the cell density in the storage suspension and the preservation period. Hepatocytes stored at 4°C in Hanks' Balanced Salt Solution (HBSS) and Williams' Medium E...
Examinations were conducted on four tongues of adult rabbits (Oryctolagus cuniculus). On the basis of observations in a scanning electron microscope (SEM) it was found that fungiform papillae in the rabbit are located on the dorsal surface of the apex and body of the tongue, in the front of the torus of the tongue and on the margins of the tongue. Moreover, fungiform papillae are located laterally...
On the root of the tongue in the rabbit there are two symmetrically located vallate papillae, covered by nonkeratinized stratified squamous epithelium. The epithelium is characterized by variable thicknesses, forming epithelial streaks of different length and irregular shape. Taste buds are found both in the epithelium covering the papillae and in the epithelium of the outer walls of the papillae...
The keton bodies are created generally in a liver, but this organ has no enzymatic system able to metabolize them. A dependence exists between the molar acetoacetate concentration and the molar ß-hydroxybutyrate concentration, and it can be an indicator of quantitive relations between NAD and NADH. Metabolic reserve can be estimated on the basis of the molar concentration of keton bodies in the arterial...
Blood was collected from bison that were selected between 1991 and 2001 for poor body condition, cachexia, lameness and balanoposthitis. Sera were tested for antibodies to bovine herpes virus type 1 (BHV-1), bovine viral diarrhoea virus (BVDV), foot-and-mouth disease virus (FMDV), parainfluenza virus type 3 (PI-3), Brucella abortus, Chlamydophila abortus, Coxiella burnetii, and Leptospira interrogans...
Peliosis hepatis (PH) is a rare condition characterized by dilatation of hepatic sinusoids and the presence of blood-filled spaces within the liver. The disease occurs mainly in subjects exposed to toxic substances or estrogens, and is often asymptomatic. A 9 year-old pekingese female dog was sent to Division of Pathology for autopsy because of sudden death of unclear cause. Autopsy revealed severe...
Prostate cancer (CaP) is a fast-growing health and social problem already representing the second leading cause of cancer-related death among men in Western countries. Lifestyle-related factors and diet are major contributors for CaP promotion. Because of unfavourable prognosis of extra-prostatic CaP, prevention is considered the best approach to fight it at present time. Green Tea Catechins (GTCs)...
Regulation of mammary gland remodeling during the lactation cycle in cattle still remains unclear. The present study focused on the role of TGF-ß1 and somatotropic pathways proteins in control of the switch between survival and death of bovine mammary epithelial cells (MEC). Expressions of TGF-ß1, TGF-ßRII, IGF-IRα, IGF-IRß, GH-R, IGFBP-3, -4, and -5 in mammary tissue explants in Holstein-Fresian...
Loss of homeostasis is a hallmark of malignant tumorigenesis and autoimmune diseases. Recent studies have implicated apoptotic cell death pathways in initiating and propagating autoimmune diseases in susceptible individuals. During malignancy, however, there is an accumulation of cells resistant to apoptosis. Intriguingly, some patients with malignant tumors develop symptoms that cannot be explained...
The intrabreed and interbreed genetic diversity of Lithuanian cattle breeds - two native, namely Lithuanian Light Grey and Lithuanian White-Backed and two modern, namely Lithuanian Red and Lithuanian Black and White was investigated by determination of genetic markers: 4 milk protein systems, Alphass1-casein, Kappa-casein, Beta-casein and Beta-lactoglobulin, which are comprised of 12 different milk...
The usefulness of endoscopic examination for the diagnosis and treatment of chronic enteritis in dogs was determined in this study. It was demonstrated, based on a clinical case, that endoscopy is essential for IBD diagnosis in dogs. Endoscopy also helps to estimate the efficiency of the treatment strategy applied. Nonspecific clinical examination results as well as a predominating lack of deviation...
One of the most promising strategies in colon cancer therapy is the sensitization of cancer cells to natural proapoptotic cytokines, such as death ligands and interferons, which are able to eliminate abnormal cells. The investigation of mechanisms determining the immune escape of cancer cells revealed the presence of antiapoptotic proteins, such as cFLIP, which inhibit cell death signal transduction...
It is generally accepted that chronic inflammatory disease, either local or generalized, is associated with higher incidence of cancer. Since inflammation is often accompanied by oxidative stress the latter was indicated as the foundation for progressive mutations leading to tumor development (proliferation, invasion, metastasis). Even though, it is very hard to demonstrate by in vitro studies the...
The aim of the study was to estimate the prevalence and localization of different tumors in the urogenital system in dogs and cats in relation to sex, age and breed of animals. The study was performed on tumors or tissue specimens from tumors of the urinary and genital system obtained during surgery from dogs and cats submitted to the Division of Pathological Anatomy, Department of Clinical Sciences...
In the present study the seroprevalence of the protozoan parasite Toxoplasma gondii infection in sheep was investigated in 6 regions of Lithuania. Blood samples were taken from 354 sheep and were tested using commercial ELISA method. The total seroprevalence of Toxoplasma gondii infection in sheep was 42.1%. Significant differences in seroprevalence were observed between age groups (P ≤ 0.05). The...
The aim of the study is the assessment of treatment effectiveness of disc extrusion with the method of ventral cervical decompression (ventral slot). Surgical procedure was performed on 15 dogs - 10 chondrodystrophoid and 5 achondrodystrophoid. Clinical signs and localization of lesions were similar to those reported earlier. All of the dogs, but one which died during the operation, were cured. Percentage...
The present study involved 180 slaughter turkey-hens of heavy Big-6 type divided into four groups (in triplicate repetition for 15 birds). All the birds were fed with the same standard full-dose mixtures in 5-stage system. The turkey-hens of groups I, II and III were given 1,2,4-triasole derivative (3-(2-pyridil)-4-phenyl-l,2,4-triasole-5-carboxylic acid), which has antibacterial, antifungal and immunomodulating...
We analysed 251 early spring and winter storage honey samples, individually collected from the apiaries of 9 districts of Małopolska province in South Poland and revealed that 51 of these specimens were contaminated with different levels of P. larvae larvae spores Among these samples 8.8% were classified as a category I contamination and 11.5% as a category II - reperesenting 22 (43.1%) and 29 (56...
This study was aimed at monitoring the effect of melatonin implants on selected hematological and biochemical indices as well as on morphology changes of lungs, liver, spleen, kidneys and brain in minks. Experiments were carried out on 300 minks aged 2 years, bred under conditions of a large-herd farm and fed identical feedstuff. Melatonin implants were inserted subcutaneously to the minks in the...
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