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This study investigates the effect of superoxide anion radical (02); hydrogen peroxide (H202), nitric oxide (NO) and peroxynitrite (ONOO), which often accompany inflamed, endotoxic or exercised muscle on insulin action in DTsatellite cells. In order to induce quiescence, rat L6 myoblasts were subjected to transition from G2/M to Gl phase by the application of serum-reduced medium. Insulin stimulating...
The purpose of this study was to determine whether inflammatory changes in uterus caused by Escherichia coli are associated with changes in nitric oxide (NO) production. Therefore, the activity of NADPH-diaphorase (NADPH-d), a histochemical marker for nitric oxide synthase (NOS), localization of inducible isoform of NOS (iNOS) and tissue content of nitrite were studied in the uterine structures after...
We previously demonstrated that both mitogenicity and anabolism in rat L6 myoblasts even in the presence of insulin could be markedly reduced by milimolar concentrations of H202, SIN-1 (3-mor- pholinosydnonimine) and SNP (sodium nitroprusside) - donors of peroxynitrite (ONOO ) and nitric oxide (NO), respectively (Orzechowski and Grzelkowska 2000). In this paper we described the results of the experiment,...
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