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Immune thrombocytopenia (ITP) is a syndrome characterized by low platelet counts and an increased risk of bleeding. For most children, ITP is a self‐limiting disease; however, for some children and most adults, thrombocytopenia can become chronic. Newer therapies for ITP include rituximab and thrombopoietin (TPO) receptor agonists. Rituximab is a useful second‐line therapy and may be splenectomy‐sparing...
Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Antibody‐mediated platelet destruction has been the prevailing hypothesis to explain ITP pathogenesis, supported by the efficacy of B‐cell depletion therapy; however, the recent success of thrombopoietin receptor agonists lends support to the notion that platelet production...
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