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A series of novel N‐triazolo‐benzene sulfonamides‐1,5‐benzodiazepines 9a–d and 10d were designed and prepared through the copper‐catalyzed azide alkyne cycloaddition click chemistry procedure, reacting the N1‐propargyl‐1,5‐benzodiazepine 2 and the N1,N5‐dipropargyl analog 6 with various benzene sulfonamide azides 8a–d. The synthesized compounds were found to show nanomolar affinity toward relevant...
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