The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
In the reaction of methyl coumalate 4 and oxalacetate with the macrophomate synthase, an aberrant product 5 was formed instead of the expected benzoate 6. The structure of 5 strongly indicates intermediacy of a bicyclic compound 10 in the extraordinary five-step transformation catalyzed by the macrophomate synthase.
Macrophomate synthase which catalyzes unusual multiple reactions from 2-pyrone (3) to macrophomic acid (1) has been purified in a homogeneous state. The macrophomate synthase is a dimeric enzyme which requires Mg 2+ as a co-factor and whose molecular mass is 40 kDa. Study on substrate specificity showed that the enzyme is capable of converting various 2-pyrones to the corresponding...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.