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Aortic stenosis (AS) is the most common native valve disease. The assessment of its severity is routinely performed using transthoracic 2D echocardiography. In particular, aortic valve area (AVA) is usually assessed by continuity equation, although this measurement relies on geometrical assumptions, or by planimetry on transesophageal echocardiography. Accordingly, the aim of this study was to develop...
Small animal positron emission tomography (PET) image quantitation is severely affected by partial volume effect (PVE) caused by the spatial resolution of PET tomographs. The aim of this work was to reduce the PVE using a modified iterative expectation maximization (EM) reconstruction algorithm. The goal of the method was to increase the accuracy of tracer concentration values in order to obtain an...
Two-dimensional echocardiography (2DE) is routinely used in clinical practice to measure left ventricular (LV) mass, dimensions, and function. The reliability of these measurements is highly dependent on the ability to obtain nonforeshortened long axis (LA) images of the left ventricle from transthoracic apical acoustic windows. Real time three-dimensional echocardiography (RT3DE) is a novel imaging...
Right ventricular (RV) volume quantification from cardiac magnetic resonance imaging is based on manual tracing of endocardial boundaries and application of geometric modeling. This procedure is subjective, time-consuming and may bias volume measurements since the right ventricle is a complex structure that is not well suited to a geometric model. We developed a technique for RV endocardial surface...
The measurement of left ventricular (LV) long axis length (LAL) is an integral part of echocardiographic evaluation of LV volume, the most important determinant of LV systolic function. LAL measurements from 2D echocardiography (2DE) are highly dependent on the ability to obtain non-foreshortened LV images. Real-time 3D echocardiography (RT3DE) could potentially overcome the effects of long-axis foreshortening,...
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