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DNA sequencing technology has played an important role on life sciences, especially Illumina's solexa sequencer. It was used for more and more genome projects. Solexa libraries were usually constructed with insert sizes of 200bp, 500bp, 2k, 5k and 10k in genome projects. It is a problem how to find the optimum combination of different insert sizes and different depth of solexa sequencing libraries...
In this paper, we describe a modified greedy search method for selecting the highest Bayesian score. Particularly, our method uses GGM to limit the searching space based on the partial correlation value. We demonstrate that our method achieved comparable results with classical method and saved ~50% of computational time. The modified greedy search method can be widely used for efficient network inference...
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