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We report a novel variant of band target entropy minimization (BTEM), adaptive band target entropy minimization (A‐BTEM), which offers an improved ability to accurately decompose mixed spectra obtained from complex multicomponent systems. Several key challenges have existed in the application of the basic BTEM approach to decompose spatially offset Raman spectra of bone underneath soft tissues and...
The decomposition of spatially offset Raman spectra for complex multilayer systems, such as biological tissues, requires advanced techniques such as multivariate analyses. Often, in such situations, the decomposition methods can reach their limits of accuracy well before the limits imposed by signal‐to‐noise ratios. Consequently, more effective reconstruction methods could yield more accurate results...
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