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The purpose of this work was to determine the effect of exogenous unesterified cholesterol provided in either artificial liposomes or LDL on bile salt synthesis by isolated rat hepatocytes. Rates of de novo synthesis were determined in the presence of 300 or 600 μM taurocholate, 600 μM taurodehydrocholate, cholate, deoxycholate or chenodeoxycholate. There was no significant difference between the...
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