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The aim of this study was to investigate the effects of GCKR polymorphism on the prevalence of overweight and obesity in Chinese female subjects using a gene-wide tagging- single nucleotide polymorphism (tSNP) strategy. We conducted a genetic association study in the Taizhou Retiree Women Cohort, a sub-cohort of the Taizhou longitudinal study. We genotyped four tSNPs (rs4425043, rs780094, rs814295,...
Recently, two polymorphisms (rs1884052 and rs3778099) of estrogen receptor α (ER-alpha) gene were identified as being associated with primary quantitative bone mineral density (BMD) in a genome-wide association (GWA) study in Framingham cohorts. In this study we aimed at investigating the association of rs1884052 and rs3778099, and another polymorphism (rs2234693) located at intron 1 of the ER-alpha...
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