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. Clear genetic differences in the susceptibility of chickens to visceral infection by Salmonella have been observed and it has been possible to identify resistant and susceptible lines of inbred chickens. We report here the results of experiments to map directly the gene(s) controlling this trait in chickens by examining crosses between highly susceptible and highly resistant lines. In the mapping...
AbstractThe gene encoding a chicken cytokine with T-cell proliferative activity was cloned, sequenced, and mapped. The results show that this cytokine is chicken IL2 and not IL15. The exon:intron structure of chicken IL2 corresponds almost exactly to those of mammalian IL2s with the exceptions of exon 2 and introns 2 and 3 which are shorter. Chicken IL2 contains five repeats of the instability motif...
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