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Antagonist therapy represents a potential treatment for extracellular matrix (ECM) metabolic imbalance via the specific binding of inflammatory factors resulting from inflammation. However, the short half‐life of antagonist bioactivity creates challenges for their clinical application. Herein, bovine serum albumin nanoparticles (BNP) encapsulating recombinant human soluble tumor necrosis factor (TNF)...
Inspired by the inflammation of the intervertebral disc degene ration microenvironment, in article number 2006333, Bruno Sarmento, Wenguo Cui, Liang Chen, and co‐workers design antagonist‐functionalized injectable porous microspheres with functions of modulating inflammation responses and regulating extracellular matrix metabolism balance to satisfy the specific demand on early‐stage restoration of...
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