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BackgroundLimited information is available about the role of adipokines in the development and progression of acute pancreatitis (AP) in dogs.
ObjectivesTo determine whether the circulating concentrations of adipokines differed between healthy dogs and dogs with AP, and whether the circulating concentrations differed between AP survivors and AP nonsurvivors.
AnimalsTwenty‐eight healthy dogs and...
Aims/hypothesis Obesity is associated with aldosterone excess, hypertension and the metabolic syndrome, but the relative contribution of aldosterone to obesity-related complications is debated. We previously demonstrated that aldosterone impairs insulin secretion, and that genetic aldosterone deficiency increases glucose-stimulated insulin secretion in vivo. We hypothesised that elimination of endogenous...
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