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Aims
Accurate classification of salivary gland neoplasms may be challenging, owing to morphological overlap, particularly in small biopsies. Recurrent translocations involving the high‐mobility group AT‐hook 2 (HMGA2) gene are present in a subset of pleomorphic adenomas (PAs) and carcinoma ex‐pleomorphic adenomas (CA ex‐PAs). The aim of this study was to evaluate immunohistochemical HMGA2 expression...
BACKGROUNDFine‐needle aspiration diagnosis of pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC) is challenging due to cytologic overlap with one another and with other salivary gland tumors having prominent epithelial and myoepithelial components. Recognition of characteristic chromosomal aberrations in several salivary gland tumors, including PA and ACC, has the potential to resolve diagnostic...
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