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Backgrounds: The relationships between insulin resistance and coronary artery disease have a great deal of attention.Methods: In order to investigate whether troglitazone, recently used for insulin resistance, has impacts upon clinical manifestations of coronary artery disease, we administered troglitazone for four months in diabetic patients with angiographically documented coronary vasospasm and...
Background: Primary gradual and prolonged dilatations cause less arterial trauma with compared with standard dilatations in elective angioplasty. The myocardium may be damaged by a sudden reperfusion. The purpose of this study was to evaluate the impact of prolonged inflation versus standard short dilatations in patients undergoing direct angioplasty.Methods: We performed a prospective analysis 70...
Backgrounds and Methods: To determine whether impaired glucose tolerance affects vasomotion of coronary artery, we evaluated maximal increases of the coronary blood flow induced by intracoronary infusion of adenosine triphosphoric acid or acetylcholine (FN or FE, respectively), using quantitative coronary arteriography and intracoronary doppler-tipped guidewire in 169 subjects, whose glucose tolerance...
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